02358nas a2200373 4500000000100000008004100001260001300042653001500055653001000070653001600080653001000096653001000106653003300116653001200149653002600161653003000187653001100217653001400228653002300242653001200265653001500277100001100292700001400303700001200317700001500329700000900344700000900353245008800362300001000450490000700460050001300467520149000480022001401970 2005 d c2005 Jun10aAdolescent10aAdult10aAge Factors10aChild10aChina10aCommunicable Disease Control10aDapsone10aDisability Evaluation10aDrug Therapy, Combination10aHumans10aIncidence10aLeprostatic Agents10aleprosy10aRecurrence1 aShen J1 aGupte M D1 aJiang C1 aManickam P1 aYu M1 aLi W00aTrends of case detection and other indicators of leprosy in China during 1985-2002. a77-820 v20 aSHEN20053 a

OBJECTIVE: To analyze the trends of case detection and other indicators of leprosy in China during 1985-2002.

METHODS: Data reported by each province were collected by China National Leprosy Database in Nanjing P.R. China. All data about registered cases were put into computer for analysis.

RESULTS: From 1985 to 2002, a total of 49,477 new leprosy cases had been detected. Among them, 69.5% were multibacillary cases and 25.4% had grade 2 disability. The child cases aged below 15 years accounted for 3.74% of total cases. Totally, 5824 cases and 303 cases relapsed after dapsone (DDS) mono-therapy and multidrug therapy (MDT), respectively. Case detection showed a marked reduction from 0.47/100,000 in 1985 to 0.18/100,000 in 1993 although there were several spurts due to operational factors. From 1994, case detection showed no significant decline. The grade 2 disability among new patients decreased from 31.4% in 1985 to 23.4% in 2002. The child case detection rate among new cases fluctuated between 2.70%-3.56% from 1999 to 2002. The incidence of relapse declined after the introduction of DDS mono-therapy. However, it increased after the introduction of MDT.

CONCLUSION: China experiences in leprosy control show that it will take a long time with continuing present leprosy control activities to bring down the case detection and other indicators to a very low level even after reaching the elimination goal of leprosy.

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