02454nas a2200493   4500000000100000008004100001653001400042653001700056653000900073653003200082653001600114653001500130653002800145653003200173653001000205653001100215653002400226653001400250653002800264653002000292653002600312653002100338653001000359653002500369653001500394653001200409653002200421653001600443653001500459100001300474700001500487700001300502700001400515700001300529700001300542700001700555700001400572245019500586856008000781300001100861490000700872520106700879022001401946       2015                            d10aTrichuris10aTrichuriasis10aSoil10aSensitivity and Specificity10aSample Size10aPrevalence10aPopulation Surveillance10aOrganizational Case Studies10aKenya10aHumans10aHookworm Infections10aHelminths10aElephantiasis, Filarial10aData Collection10aCost-Benefit Analysis10aChild, Preschool10aChild10aAscaris lumbricoides10aAscariasis10aAnimals10aAncylostomatoidea10aAge Factors10aAdolescent1 aSmith JL1 aSturrock H1 aAssefa L1 aNikolay B1 aNjenga S1 aKihara J1 aMwandawiro C1 aBrooker S00aFactors associated with the performance and cost-effectiveness of using lymphatic filariasis transmission assessment surveys for monitoring soil-transmitted helminths: a case study in Kenya.  uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347340/pdf/tropmed-92-342.pdf  a342-530 v923 a<p>Transmission assessment surveys (TAS) for lymphatic filariasis have been proposed as a platform to assess the impact of mass drug administration (MDA) on soil-transmitted helminths (STHs). This study used computer simulation and field data from pre- and post-MDA settings across Kenya to evaluate the performance and cost-effectiveness of the TAS design for STH assessment compared with alternative survey designs. Variations in the TAS design and different sample sizes and diagnostic methods were also evaluated. The district-level TAS design correctly classified more districts compared with standard STH designs in pre-MDA settings. Aggregating districts into larger evaluation units in a TAS design decreased performance, whereas age group sampled and sample size had minimal impact. The low diagnostic sensitivity of Kato-Katz and mini-FLOTAC methods was found to increase misclassification. We recommend using a district-level TAS among children 8-10 years of age to assess STH but suggest that key consideration is given to evaluation unit size.</p>
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