01379nas a2200253   4500000000100000008004100001653001100042653002400053653001600077653002500093653001200118653001500130100001700145700001400162700001400176700002100190700002000211700001100231700002100242700001300263245006200276520077300338022001401111       2016                            d10aSaliva10aReactional episodes10aOral cavity10aMycobacterium leprae10aleprosy10aImmunology1 aRodrigues GA1 aQUALIO NP1 aMacedo LD1 aInnocentini LMAR1 aRibeiro-Silva A1 aFoss N1 aCipriani Frade M1 aMotta AC00aThe oral cavity in leprosy: what clinicians need to know.3 a<p>Leprosy is a chronic infectious disease caused by Mycobacterium leprae, a bacillus that has a tropism for skin and peripheral nerves. Leprosy treatment is based on a multidrug therapy established by the World Health Organization in 1982 and, despite its widespread use, Brazil ranks second worldwide in numbers of cases. Oral involvement in leprosy has been poorly described in the literature, and few studies have shown that although the bacillus is found in mucosa, specific leprosy lesions are rare and affect patients with advanced stages of the disease. This review aimed to assess the literature on oral manifestations in leprosy and the aspects involving oral cavity in leprosy pathogenesis. This article is protected by copyright. All rights reserved.</p>
  a1601-0825