01553nas a2200421   4500000000100000008004100001260001300042653001800055653001900073653001100092653001300103653001100116653001400127653001000141653001200151653000900163653002800172653002500200653003000225653001600255653003200271653002800303100001300331700001200344700001300356700001300369700001200382700001100394700001200405700001200417245008900429856005100518300000900569490000700578050003200585520050000617022001401117       2002                            d  c2002 Mar10aBase Sequence10aDNA, Bacterial10aFemale10agenotype10aHumans10aIncidence10aKorea10aleprosy10aMale10aMolecular Sequence Data10aMycobacterium leprae10apolymerase chain reaction10aProbability10aSensitivity and Specificity10aTandem Repeat Sequences1 aChae G T1 aLee S B1 aKang T J1 aShin H K1 aKim J P1 aKo Y H1 aKim S H1 aKim N H00aTyping of clinical isolates of Mycobacterium leprae and their distribution in Korea.  uhttps://leprosyreview.org/article/73/1/00-0006  a41-60 v73  aInfolep Library - available3 a<p>Although there is no genetic diversity in isolates of Mycobacterium leprae, the variance of tandem repeats in the rpoT gene was recently demonstrated. We have typed clinical isolates of M. leprae in Korea using difference of the tandem repeats in the rpoT gene. Among 69 patients, 65 Korean isolates (94.2%) demonstrated four copies of the 6 bp tandem repeat (GACATC) in the rpoT gene, and incidences of three copies were found in only two Koreans and two foreigners (2.9%, respectively).</p>  a0305-7518