02512nas a2200325   4500000000100000008004100001653003100042653001400073653001500087653001200102653001000114100001200124700001100136700001100147700001300158700001100171700001600182700001100198700001000209700001000219700001100229700001100240700001000251245014200261856012100403300001200524490000700536520162900543022001402172       2016                            d10aActivities of Daily Living10aCognition10aGeriatrics10aleprosy10aKorea1 aKang KW1 aChoi S1 aShin M1 aKweon SS1 aPark H1 aDong-Chan O1 aChoi M1 aLee M1 aKim D1 aChoi K1 aBaek S1 aKim B00aCognitive function and activities of daily living in people affected by leprosy: A cross-sectional, population-based, case-control study.  uhttp://www.neurologyindia.com/article.asp?issn=0028-3886;year=2016;volume=64;issue=4;spage=656;epage=660;aulast=Kang  a656-6600 v643 a<p><strong>OBJECTIVES: </strong>There has been controversy regarding whether or not people affected by leprosy have more cognitive dysfunction than healthy individuals. The purpose of this study was to assess cognitive functions and activities of daily living (ADL) in people affected by leprosy relative to a control population living in rural areas.</p>

<p><strong>MATERIALS AND METHODS: </strong>We assessed cognitive functions and ADL using the Korean Mini-Mental State Examination (K-MMSE), Korean Dementia Screening Questionnaire (KDSQ), and Seoul-Instrumental ADL (S-IADL). Higher scores of K-MMSE and lower scores of both KDSQ and S-IADL are indicative of better functioning. We assessed 224 persons living in Sorokdo who were affected by leprosy and 448 age- and gender-matched control subjects living in Namwon of the Chonbuk province.</p>

<p><strong>RESULTS: </strong>After adjusting for age, gender, and educational status, the K-MMSE score was found to be significantly higher in people affected by leprosy than in control subjects (23.14 ± 4.89 vs. 22.25 ± 4.62, respectively, P = 0.022). Items related to memory in the KDSQ showed no differences between the groups, but people affected by leprosy had a better score in division for other cognitive functions than controls. On items related to ADL in the KDSQ and S-IADL, people affected by leprosy performed significantly worse compared with controls.</p>

<p><strong>CONCLUSIONS: </strong>Our results suggest that although people affected by leprosy have a lower capacity of ADL, they may have better cognitive functions than normal controls.</p>
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