01761nas a2200373   4500000000100000008004100001260001300042653001100055653001500066653001100081653001100092653002800103653001200131653002500143653002500168653002100193653001700214653000900231653002400240653003200264653003000296653000900326100001300335700001400348700001700362700001200379245013200391856005100523300001000574490000700584050003200591520075000623022001401373       2002                            d  c2002 Mar10aCarbon10aElasticity10aFemale10aHumans10aInjections, Intravenous10aleprosy10aLeprosy, lepromatous10aLeprosy, Tuberculoid10aLymphatic System10aLymphography10aMale10aProspective Studies10aSensitivity and Specificity10aSeverity of Illness Index10aSkin1 aRyan T J1 aJones R L1 aMortimer P S1 aSingh G00aLymphatics in leprosy: relationship to elastic fibres and observations following intra-lesional injections of colloidal carbon.  uhttps://leprosyreview.org/article/73/1/00-0008  a52-630 v73  aInfolep Library - available3 a<p>An investigation of skin lymphatics in leprosy has been undertaken. Examination of 62 skin biopsies from 31 patients with various classifications of leprosy has revealed dilated initial lymphatics within granulomas of lepromatous leprosy, but no significant abnormalities in non-lepromatous disease or in non-granulomatous skin. Colloidal carbon injected intra-lesionally failed to appear within granulomas, but could be seen in lymphatics in non-granulomatous dermis. Elastic fibres were also absent within granulomas. AFB were clearly identified within endothelial cells of initial lymphatics. We suggest lymphatic malfunction may be compartmental, existing only within the granulomas and not in the surrounding normal appearing dermis.</p>  a0305-7518