02144nas a2200205   4500000000100000008004100001100001200042700001400054700001400068700001600082700001500098700001500113700001500128245009200143856007800235300001300313490000700326520159100333022001401924       2016                            d1 aTabah E1 aNsagha DS1 aBissek AZ1 aNjamnshi AK1 aBratschi M1 aPluschke G1 aUm Boock A00aBuruli ulcer in Cameroon: The development and impact of the national control programme.  uhttp://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0004224  ae00042240 v103 a<p><strong>BACKGROUND: </strong>Cameroon is endemic for Buruli ulcer (BU) and organised institutional BU control began in 2002. The objective was to describe the evolution, achievements and challenges of the national BU control programme (NBUCP) and to make suggestions for scaling up the programme.</p>

<p><strong>METHODS: </strong>We analysed collated data on BU from 2001 to 2014 and reviewed activity reports NBUCP in Cameroon. Case-detection rates and key BU control indicators were calculated and plotted on a time scale to determine trends in performance. A linear regression analysis of BU detection rate from 2005-2014 was done. The regression coefficient was tested statistically for the significance in variation of BU detection rate.</p>

<p><strong>PRINCIPAL FINDINGS: </strong>In 14 years of BU control, 3700 cases were notified. The BU detection rate dropped significantly from 3.89 to 1.45 per 100 000 inhabitants. The number of BU endemic health districts rose from two to 64. Five BU diagnostic and treatment centres are functional and two more are planned for 2015. The health system has been strengthened and BU research and education has gained more interest in Cameroon.</p>

<p><strong>CONCLUSION/SIGNIFICANCE: </strong>Although institutional BU control Cameroon only began 30 years after the first cases were reported in 1969, a number of milestones have been attained. These would serve as stepping stones for charting the way forward and improving upon control activities in the country if the major challenge of resource allocation is dealt with.</p>
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