01284nas a2200169   4500000000100000008004100001653002000042653001400062653000800076100001300084700001500097245006700112856005100179300001200230490000700242520086500249       2015                            d10aT-cell activity10aHistology10aCMI1 aKhodke A1 aShetty V P00aType 1 reaction masquerading clinically as ENL: A Case Report.  uhttps://leprosyreview.org/article/86/2/19-1963  a202-2050 v863 a<p><strong>Summary</strong>: Attention is drawn to a Type 1 reaction masquerading clinically as ENL. Histology showed no evidence of ENL but suggested heightened T-cell activity (CMI), a characteristic feature of Type 1 reaction. We present a case of a 29 year old man diagnosed as lepromatous leprosy with recurrent Type 2 reaction treated with thalidomide for 2 years. The patient was referred to our institute from a teaching hospital. Skin biopsies were carried out during two separate eruptive episodes 2 months apart. Histopathology showed heightened T-cell activity, but no evidence of ENL.</p>

<p><strong>Conclusion</strong>: Attention is drawn to a Type 1 reaction masquerading clinically as ENL. Histology showed no evidence of ENL but suggested heightened T-cell activity (CMI), a characteristic feature of Type 1 reaction.</p>

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