00880nas a2200229 4500000000100000008004100001260000900042653001800051653001400069653002500083653002100108653002200129653001300151653002500164100001400189700001600203245007400219300001600293490000600309520032100315022001400636 2001 d c200110aCell Membrane10aCell Wall10aEvolution, Molecular10aGenes, Bacterial10aGenome, Bacterial10aGenomics10aMycobacterium leprae1 aVissa V D1 aBrennan P J00aThe genome of Mycobacterium leprae: a minimal mycobacterial gene set. aREVIEWS10230 v23 a

Comparison of the recently sequenced genome of the leprosy-causing pathogen Mycobacterium leprae with other mycobacterial genomes reveals a drastic gene reduction and decay in M. leprae affecting many metabolic areas, exemplified by the retention of a minimal set of genes required for cell-wall biosynthesis.

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