01368nas a2200325   4500000000100000008004100001260001700042653002800059653001000087653000900097653001100106653001100117653001500128653001200143653000900155653001600164653002600180653001500206653002200221100001600243700001600259700002200275700002300297245007900320300001100399490000700410050003200417520057900449022001401028       2001                            d  c2001 Apr-Jun10aAdministration, Topical10aAdult10aAged10aFemale10aHumans10aKetanserin10aleprosy10aMale10aMiddle Aged10aSerotonin Antagonists10aSkin Ulcer10aTreatment Outcome1 aSalazar J J1 aSerrano G G1 aLeon-Quintero G I1 aTorres-Mendoza B M00aUse of topical ketanserin for the treatment of ulcers in leprosy patients.  a103-100 v73  aInfolep Library - available3 a<p>A comparative study was carried out in which 66 leprosy patients with ulcers were randomly divided in two groups of 33 patients each: Group A (experimental group) was treated with ketanserin gel (2%) and group B with clioquinol cream and/or Lassar paste during a three month period. At the end of the study, when ulcer sizes in the two groups were compared, the group treated with topical ketanserin showed superior results (p < 0.001 using Kolmogorov-Smirnov's test). We conclude that the drug is useful as coadjuavant treatment for healing ulcers in these patients.</p>  a0254-9395