01404nas a2200421   4500000000100000008004100001260001300042653000900055653002900064653001100093653002400104653002600128653001800154653001100172653001100183653002300194653002500217653000900242653001600251653002500267653001300292653001900305653003600324653001500360653001500375653001500390653001500405100001400420700001700434700001700451700001300468245005800481856004100539300001100580490000700591520037000598022001400968       2000                            d  c2000 Dec10aAged10aAnti-Inflammatory Agents10aBrazil10aDisease Progression10aEndothelium, Vascular10aFatal Outcome10aFemale10aHumans10aLeprostatic Agents10aLeprosy, lepromatous10aMale10aMiddle Aged10aMycobacterium leprae10aNecrosis10aPentoxifylline10aPlatelet Aggregation Inhibitors10aPrednisone10aSkin Ulcer10aThrombosis10aVasculitis1 aSouza C S1 aRoselino A M1 aFigueiredo F1 aFoss N T00aLucio's phenomenon: clinical and therapeutic aspects.  uhttp://ila.ilsl.br/pdfs/v68n4a03.pdf  a417-250 v683 a<p>We report four cases of necrotizing reactions of the Lucio's phenomenon type, an entity rarely observed in Brazil despite the high prevalence of leprosy. Clinical, histopathological and therapeutic aspects are described and compared to those reported in the literature for cases classified as diffuse, non-nodular lepromatous leprosy with Lucio's phenomenon.</p>  a0148-916X