01559nas a2200313 4500000000100000008004100001260001700042653001100059653001100070653002000081653002500101653003200126653000900158653001600167653000900183653001900192653002900211100001100240700001200251700001300263700001300276700001300289700001400302245006800316300001000384490000700394520083000401022001401231 2013 d c2013 Mar-Apr10aBiopsy10aHumans10aImmunochemistry10aLeprosy, lepromatous10aLymphoma, T-Cell, Cutaneous10aMale10aMiddle Aged10aSkin10aSkin Neoplasms10aT-Lymphocytes, Cytotoxic1 aMaio P1 aBento D1 aVieira R1 aAfonso A1 aSachse F1 aKutzner H00aNon Hodgkin T cell lymphoma: an atypical clinical presentation. a264-70 v883 a

Cytotoxic lymphomas comprise a spectrum of peripheral T-cell lymphomas that can have a initial or late cutaneous presentation. We describe a 46-year-old man from Cape Verde, with a dermatosis involving his face and trunk, consisting of monomorphic papules with a smooth surface and both motor and sensory polyneuropathy.The hypothesis of leprosy was supported by the clinical and initial hystopathological findings and the patient was referred to our hospital with suspected Hansen's disease. In the new skin and lymph node biopsies a lymphocyte population was identified whose immunohystochemistry study allowed the diagnosis of T-cell lymphoma with expression of cytotoxic markers. The patient was started on chemotherapy with initial remission of the skin lesions but, subsequently, progression of systemic disease.

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