01035nas a2200253   4500000000100000008004100001653001200042653002000054653001200074653001000086100001500096700001300111700001300124700001600137700002000153700001000173700001300183700001300196245006900209856007500278300001100353490000700364520041000371       1981                            d10aleprosy10aDrug Resistance10aDapsone10aChina1 aWenzhong L1 aGanYun Y1 aHeying W1 aShunzhang Y1 aWu Qinxue1 ZYMB1 aLin M1 aYongfa Z1 aBukuan M00a[Clinical and experimental studies on sulfone resistant leprosy]  uhttp://manu16.magtech.com.cn/Jwk_cmazp/EN/abstract/abstract20400.shtml  a75-79 0 v143 aThe most solid foundation for leprosy control today rests on the effectiveness of sulfone therapy.However,the emergence of dapsone resistance with increasing frequency raises a serious problem for program mes of treatment and control of leprosy.Twelve cases of dapsone resistant leprosy were proved by clinical trials and/or foot-pad tests of mice in Qinhu Leprosarium during the period of 1975 to 1979.