01284nas a2200217   4500000000100000008004100001653003400042653003800076653001200114100001400126700001400140700001400154700001800168700001200186245008000198856005000278300001200328490000600340050001500346520070500361       1990                            d10aHousehold contact examination10aPurified Protein Derivative (PPD)10aleprosy1 aDuppre NC1 aAlvim MFS1 aGallo MEN1 aCosta Nery JA1 aSarno E00aFatores envolvidos na reatividade do PPD em pacientes com doença de Hansen  uhttp://www.scielo.br/pdf/csp/v6n2/v6n2a06.pdf  a175-1850 v6  aDUPPRE19903 aPPD (Purified Protein Derivative) was injected intradermally in 236 leprosy patients (138 of multibacillary form and 98 paucibacillary), 297 healthy household leprosy contacts. The less reactive population to PPD was composed of multibacillary patients with a positivity rate of 42%, 62,2% for paucibacillary and 63,2% for contacts. Among the multibacillary patients the BI (Bacteriological index) seems to interfere with PPD reactivity. It was found a significative association between negative response to PPD and BI greater than 3+ (p<5). It was observed high positivity rate to PPD in healthy household contacts (61,0%) and paucibacillary leprosy patients (65,3%) with positive Mitsuda Skin test.