00760nas a2200217   4500000000100000008004100001260001600042653002200058653001100080653001200091653001300103653002500116100001200141700001600153245006200169300001100231490000700242050001500249520026400264022001400528       2001                            d  c2001 May 1510aGenome, Bacterial10aHumans10aleprosy10aMutation10aMycobacterium leprae1 aYoung D1 aRobertson B00aGenomics: leprosy - a degenerative disease of the genome.  aR381-30 v11  aYOUNG 20013 a<p>Analysis of the genome of the leprosy bacillus uncovers evidence of extensive deletion and inactivation of genes. Secluded in a specialised niche, it has discarded much of its genetic heritage, though retaining just enough to be a major human pathogen.</p>  a0960-9822