02652nas a2200445   4500000000100000008004100001260001300042653000900055653002500064653001100089653001100100653001200111653000900123653001600132653001500148653002200163653002700185653003000212653001000242653003100252100001100283700001000294700001200304700001100316700001100327700001100338700000800349700001100357700001000368700001500378700001100393700001100404245005800415856005100473300001000524490000700534050001400541520163700555022001402192       2012                            d  c2012 Dec10aAged10aCase-Control Studies10aFemale10aHumans10aleprosy10aMale10aMiddle Aged10aPrevalence10aRepublic of Korea10aRestless legs syndrome10aSeverity of Illness Index10aSleep10aSurveys and Questionnaires1 aChoi S1 aKim B1 aKweon S1 aShin M1 aPark J1 aSong H1 aO D1 aKwon H1 aLee M1 aYong-Jun L1 aJung P1 aPark H00aRestless legs syndrome in people affected by leprosy.  uhttps://leprosyreview.org/article/83/4/36-3369  a363-90 v83  aCHOI 20123 a<p><b>OBJECTIVES: </b>Restless legs syndrome (RLS) is one of the most commonly encountered sleep disorders. The prevalence of RLS and its association'with leprosy have not previously been elucidated. The aims of this study were to investigate the prevalence of RLS in people affected by leprosy and to determine the presence and amount of sleep disruption in leprosy affected people with RLS.</p><p><b>DESIGN: </b>Each leprosy-affected person was matched to two healthy controls for age and sex. A total of 236 leprosy-affected people who lived in Sorokdo and 472 healthy control subjects who lived in Namwon were included in this study. A diagnosis of RLS and a severity assessment were made using the criteria described by the International Restless Legs Syndrome Study Group.</p><p><b>RESULTS: </b>The prevalence of RLS was significantly higher in people affected by leprosy (60/236; 25.4%) than in controls (42/472; 8.8%). Pittsburgh Sleep Quality Index (PSQI) global score was higher in leprosy-affected people than in controls. No significant difference was found between leprosy-affected people and controls with regard to the severity of RLS. Leprosy-affected people with RLS had a poorer sleep quality (higher PSQI global score) than those without RLS, but the Geriatric Depression Scale was not different between leprosy-affected people with RLS and those without RLS.</p><p><b>CONCLUSIONS: </b>The frequency of RLS among leprosy-affected people was significantly higher than that of RLS in the general population. Leprosy-affected people should be examined for RLS and treatment for RLS can potentially improve sleep.</p>  a0305-7518