02108nas a2200433   4500000000100000008004100001260001700042653001500059653001000074653000900084653001500093653001100108653001000119653001100129653001600140653002700156653002500183653001100208653001500219653001200234653002400246653000900270653001600279653001600295653001500311653003000326100001100356700001400367700001500381700001600396700001600412700001700428700001300445245009700458300001000555490000700565520108800572022001401660       1992                            d  c1992 Sep-Oct10aAdolescent10aAdult10aAged10aBiomarkers10aBrazil10aChild10aFemale10aHepatitis B10aHepatitis B Antibodies10aHepatitis B Antigens10aHumans10aInpatients10aleprosy10aLeprosy, Borderline10aMale10aMiddle Aged10aOutpatients10aPrevalence10aSeroepidemiologic Studies1 aRosa H1 aCosta A P1 aFerraz M L1 aPedroza S C1 aAndrade A L1 aMartelli C M1 aZicker F00aAssociation between leprosy and hepatitis B infection. A survey in Goiânia, central Brazil.  a421-60 v343 a<p>This investigation presents the results of hepatitis B virus screening among leprosy patients conducted in central Brazil as a preliminary information for a HBV vaccination programme. The main objectives were to assess the seroprevalence of HBV serum markers among lepromatous patients and to analyse institutionalization as risk factor for HBV infection in this population. Two groups of lepromatous patients were studied, 83 outpatients and 171 institutionalized ones. Screening for HBV serum markers included the detection of HBsAg, anti-HBc by radioimmune assay (RIA). The prevalence of carrier state (HBsAg) was 4.8% and 8.8% among outpatients and institutionalized, respectively, (p > 0.05). Seroprevalence of exposure (all markers) was statistically significant different between outpatients (16.9%) and institutionalized ones (50.3%). Institutionalized patients had an almost four fold risk of HBV infection when compared to the outpatients, and the highest risks were among patients with more than 21 years of residence in the colony, after adjusting for age and sex.</p>  a0036-4665