01948nas a2200337 4500000000100000008004100001260001300042653001500055653002500070653002800095653002100123653001300144653001100157653002900168653003300197653002500230653000900255653001400264653002600278653002900304653001600333100001400349700001200363700001200375700001400387245011800401300000900519490000700528520106100535022001401596 2013 d c2013 Jan10aAdolescent10aAntiprotozoal Agents10aDiagnosis, Differential10aEndemic Diseases10aEthiopia10aHumans10aLeishmaniasis, Cutaneous10aLeishmaniasis, Mucocutaneous10aLeprosy, Tuberculoid10aMale10aMeglumine10aMeglumine Antimoniate10aOrganometallic Compounds10aYoung Adult1 aDassoni F1 aAbebe Z1 aNaafs B1 aMorrone A00aCutaneous and mucocutaneous leishmaniasis resembling borderline-tuberculoid leprosy: a new clinical presentation? a74-70 v933 a

Both cutaneous and mucocutaneous leishmaniasis are endemic in Northern Ethiopia. The different clinical presentations depend on the responsible organism and the host's immune response. Localized cutaneous leishmaniasis is the type most frequently seen. Diffuse cutaneous leishmaniasis is relatively rare and usually associated with mucous membrane involvement. Diffuse cutaneous leishmaniasis presents with multiple lesions, can be difficult to diagnose and responds less favourably to treatment. We report here 2 patients with unusual presentations of diffuse cutaneous leishmaniasis presenting with large hypopigmented skin lesions mimicking borderline-tuberculoid leprosy. To our knowledge this presentation has not been described before and may present difficulties in making a definite diagnosis in regions where both leprosy and cutaneous leishmaniasis are endemic. Lepromatous leprosy and diffuse cutaneous leishmaniasis are regularly confused, particularly when no skin smears for acid-fast bacillus or Leishman-Donovan bodies are performed.

 a1651-2057