01237nas a2200265   4500000000100000008004100001260001300042653001200055653001000067653002800077653003100105653001300136653002100149653003000170653001000200653001900210100001500229700001700244700001800261245010600279300001100385490000800396520055300404022001400957       2001                            d  c2001 May10aAnimals10aIleum10aLeukocytes, Mononuclear10aMycobacterium tuberculosis10aNeuritis10aParatuberculosis10apolymerase chain reaction10aSheep10aSheep Diseases1 aGwozdz J M1 aThompson K G1 aManktelow B W00aLymphocytic neuritis of the ileum in sheep with naturally acquired and experimental paratuberculosis.  a317-200 v1243 a<p>In a comparison of natural and experimentally induced ovine paratuberculosis, aggregations of mononuclear inflammatory cells were detected around nerves in the ileal submucosa in eight of 12 sheep with natural disease and in five of 14 animals with unequivocal experimental paratuberculosis. Such lesions were not seen in 10 other sheep that, despite attempted experimental infection, remained free from the disease, as judged clinically, histopathologically and by PCR assay. The lesions described resembled those observed in human leprosy.</p>  a0021-9975