01523nas a2200313 4500000000100000008004100001260001700042653001100059653002300070653003800093653001100131653001900142653001600161653003700177653001300214653001900227653002200246100001400268700001200282700001500294700001500309700001300324700001200337245013500349300000900484490000700493520069500500022001401195 2013 d c2013 Jan-Feb10aFemale10aFumarate Hydratase10aGenetic Predisposition to Disease10aHumans10aLeiomyomatosis10aMiddle Aged10aNeoplastic Syndromes, Hereditary10aPedigree10aSkin Neoplasms10aUterine Neoplasms1 aMandal RK1 aKoley S1 aBanerjee S1 aKabiraj SP1 aGhosh SK1 aKumar P00aFamilial leiomyomatosis cutis affecting nine family members in two successive generations including four cases of Reed's syndrome. a83-70 v793 a

Reed's syndrome or familial leiomyomatosis cutis et uteri is an autosomal dominant disorder, characterized by multiple cutaneous and uterine leiomyomas. We report here a case of a 53-year-old woman who presented to us with multiple painful nodules over different parts of her body. Based on the histopathological examination, imaging, and past medical records, a diagnosis of Reed's syndrome was made. Three of her sisters had similar disease. Subsequently, it was found that a total of nine members of their family in two successive generations were affected with cutaneous leiomyomas. The present case series has been reported for its interesting clinical presentations and rarity.

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