01488nas a2200265   4500000000100000008004100001260001300042653002300055653002000078653001100098653002300109653001200132653002500144653001600169100001300185700001700198700001100215245009600226856004800322300001000370490001600380050001600396520079600412022001401208       2012                            d  c2012 Dec10aBacterial Vaccines10aContact Tracing10aHumans10aLeprostatic Agents10aleprosy10aMycobacterium leprae10aVaccination1 aDuthie M1 aSaunderson P1 aReed S00aThe potential for vaccination in leprosy elimination: new tools for targeted interventions.  uhttp://www.scielo.br/pdf/mioc/v107s1/27.pdf  a190-60 v107 Suppl 1  aDUTHIE 20123 a<p>Despite the huge effort and massive advances toward the elimination of leprosy over the last two decades, the disease has proven stubborn; new case detection rates have stabilised over the last few years and leprosy remains endemic in a number of localised regions. The American Leprosy Missions and Infectious Disease Research Institute have undertaken a large research effort aimed at developing new tools and a vaccine to continue the push for leprosy elimination. In this paper, we outline our strategy for the integration of rapid diagnostic tests and lab-based assays to facilitate the detection of early or asymptomatic leprosy cases, as well as the efficient and focused implementation of chemoprophylaxis and immunisation to intervene in leprosy development and transmission.</p>  a1678-8060