01921nas a2200433 4500000000100000008004100001260001700042653001500059653001000074653000900084653002200093653002600115653001300141653002500154653001000179653002700189653001100216653001500227653001600242653001100258653001200269653000900281653001600290653001600306653002600322653001600348100001500364700001300379700001500392700001300407700002100420700001400441245011600455300001000571490000700581050003200588520085300620022001401473 2000 d c2000 Oct-Dec10aAdolescent10aAdult10aAged10aAged, 80 and over10aAnti-Bacterial Agents10aBacteria10aBacterial Infections10aChild10aDiabetes Complications10aFemale10aFoot Ulcer10aGentamicins10aHumans10aleprosy10aMale10aMiddle Aged10aPenicillins10aRetrospective Studies10aSuppuration1 aEbenezer G1 aDaniel S1 aSuneetha S1 aReuben E1 aPartheebarajan S1 aSolomon S00aBacteriological study of pus isolates from neuropathic plantar ulcers associated with acute inflammatory phase. a443-90 v72 aInfolep Library - available3 a
In this retrospective study, sensitivity of organisms cultured from ulcers of leprosy patients without and with diabetes mellitus, diabetic patients without leprosy and patients with ulcers from other causes was examined. The profile of organisms grown from these groups of patients did not differ significantly. However, there was a high prevalence of organisms like Proteus, E. coli and Enterococcus in the ulcers of leprosy patients indicating faecal contamination of the ulcers. Co-trimaxazole and tetracycline were of little value in the treatment of these ulcers. We therefore recommend that in situations where there is no culture facility, the patients be started on a course of penicillin and gentamycin. If these antibiotics fail, it would be necessary to use more advanced antibiotics like norfloxacin, amikacin and ciprofloxacin.
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