01790nas a2200409   4500000000100000008004100001260001300042653001500055653001000070653001600080653000900096653001100105653000900116653000900125653001100134653001200145653000900157653001600166653001100182653002300193653001600216653002400232653002300256653001300279653001000292100001400302700001500316700001900331700001300350245008800363856004100451300001000492490000700502050001500509520084200524022001401366       2000                            d  c2000 Sep10aAdolescent10aAdult10aAge Factors10aAged10aFemale10aFoot10aHand10aHumans10aleprosy10aMale10aMiddle Aged10aNylons10aObserver Variation10aOccupations10aRegression Analysis10aSensory Thresholds10aThailand10aUlcer1 aBirke J A1 aBrandsma W1 aSchreuders T A1 aPiefer A00aSensory testing with monofilaments in Hansen's disease and normal control subjects.  uhttp://ila.ilsl.br/pdfs/v68n3a07.pdf  a291-80 v68  aBIRKE 20003 a<p>Sensory testing with Semmes-Weinstein filaments was conducted on: 112 normal subjects to determine the effects of age, gender and occupation on threshold perception, 27 Hansen's disease (HD) patients to determine inter-observer and intra-observer reliability of testing, and 101 patients with HD and a history of hand and/or foot ulceration to identify thresholds for injury risk. Filament thresholds were found related to age (p < 0.002) and occupation (p < 0.001) but not gender (p > 0.1). Inter-observer and intra-observer reliability was found to be high (intraclass correlation coefficient = 0.88-0.93). The 4.93 (7.0-7.7 g) filament had 97% sensitivity and 100% specificity for identifying a history of foot injuries, and the 4.17 (1.2-1.6 g) filament had 100% sensitivity and 100% specificity for identifying hand injuries.</p>  a0148-916X