01611nas a2200277   4500000000100000008004100001260001600042653001600058653002300074653001200097653001000109653003000119653002700149100002500176700001900201700001100220700001400231700002500245700001900270700001700289245011200306856017700418050002300595520070100618022001401319       2012                            d  c2012 Jun 1510aThalidomide10aPulmonary Embolism10aleprosy10aJapan10aErythema Nodosum Leprosum10aDeep venous thrombosis1 aHebe Petiti-Martin G1 aVillar-Buill M1 aHera I1 aFuertes L1 aBurgués-Calderón M1 aRivera-Díaz R1 aVanaclocha F00aDeep Vein Thrombosis in a Patient With Lepromatous Leprosy Receiving Thalidomide to Treat Leprosy Reaction.  uhttp://www.gefaesse.at/download/12_aktuelle_literatur-17-04-2012/Deep-venous-thrombosis-and-pulmonary-embolism-secondary-to-co-administration-of-thalidomide-and-oral---.pdf  aPETITI MARTIN 20123 a<p>Thalidomide is the treatment of choice for severe or recurrent erythema nodosum leprosum. Its use has been associated with deep vein thrombosis in patients with blood disorders, however, particularly when used in combination with corticosteroids or chemotherapy. We describe a case of deep vein thrombosis in a 43-year-old man with lepromatous leprosy who was being treated with thalidomide and prednisone for a type 2 leprosy reaction (erythema nodosum leprosum); the patient also had transiently positive antiphospholipid antibody results. We stress the importance of considering deep vein thrombosis, a potentially fatal complication, in dermatology patients treated with thalidomide.</p>
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