01972nas a2200325   4500000000100000008004100001260004500042653001100087653001600098653001200114653003000126653002100156653002000177653001100197653001900208653002300227653002500250653000900275653001600284653001600300653001500316653001300331100002100344700001400365245011000379300001200489490000700501520112400508022001401632       2012                            d  c2012 JunbBlackwell Publishing LtdaS.l.10aBiopsy10aClofazimine10aDapsone10aDrug Therapy, Combination10aErythema Nodosum10aGlucocorticoids10aHumans10aLeg Dermatoses10aLeprostatic Agents10aLeprosy, lepromatous10aMale10aMiddle Aged10aPhilippines10aPrednisone10aRifampin1 aYuchua-Guillen A1 aDofitas B00aAtypical Hansen's disease presenting as florid verrucous plaques on the lower extremities: a case report.  a697-7010 v513 a<p><b>BACKGROUND: </b>Verrucous leprosy is rare, with only 18 cases reported in the literature. Visceral involvement is frequent but often overlooked, causing significant morbidity and mortality.</p><p><b>CASE REPORT: </b>A 45-year-old Filipino male with a 16-year history of hyperpigmented, hypoesthetic plaques, amputated digits, enlarged ulnar nerve, and cardiovascular congestion was diagnosed with Hansen's disease-lepromatous type. He had multiple cauliflower-like nodules and plaques with foul-smelling discharge on the lower extremities presenting a diagnostic dilemma. After an exhaustive search, the causative agent for these verrucous nodules was confirmed to still be Mycobacterium leprae. In addition, he had glomerulonephritis, hypertension, congestive heart failure, deep venous thrombosis, neuritis, keratitis, and glaucoma, which are all complications of advanced leprosy and multiple attacks of erythema nodosum leprosum reactions.</p><p><b>CONCLUSION: </b>He was treated with a multibacillary regimen of Rifampicin, Dapsone, Clofazimine, and systemic corticosteroids, with remarkable improvement.</p>  a1365-4632