01095nas a2200265   4500000000100000008004100001260001300042653001700055653001100072653001200083653001600095653001300111653000900124653001400133653001300147100001200160700001800172700002500190700001700215245008400232300001000316490000700326520048200333022001400815       2001                            d  c2001 Mar10aAutoimmunity10aHumans10aleprosy10aMelanocytes10aMelanoma10aSkin10aSymbiosis10aVitiligo1 aDas P K1 aWijngaard R M1 aWankowicz-Kalinska A1 aLe Poole I C00aA symbiotic concept of autoimmunity and tumour immunity: lessons from vitiligo.  a130-60 v223 a<p>Vitiligo is a skin disease in which melanocytes (MCs) are eradicated from lesional epidermis, resulting in disfiguring loss of pigment. MCs are destroyed by MC-reactive T cells, as well as other non-immune and immune components. Similarities exist between the autoimmunity observed in vitiligo and the tumour immunity observed in melanoma immuno-surveillance. An analysis of these mechanisms might lead to the development of new therapies for both vitiligo and melanoma.</p>  a1471-4906