01343nas a2200253   4500000000100000008004100001260004900042653001200091653002400103653002300127653001100150653001200161653002500173653002000198100001200218700001300230700001500243245013900258856005100397300001100448490000700459520060900466022001401075       2011                            d  c2011 DecbLEPRA Health in ActionaColchester10aAnimals10aAntigens, Bacterial10aBacterial Proteins10aHumans10aleprosy10aMycobacterium leprae10aSerologic Tests1 aGeluk A1 aDuthie M1 aSpencer JS00aPostgenomic Mycobacterium leprae antigens for cellular and serological diagnosis of M. leprae exposure, infection and leprosy disease.  uhttps://leprosyreview.org/article/82/4/40-2421  a402-210 v823 a<p>Due to changes in leprosy control programs and the special expertise required for diagnosis, the need for simple rapid diagnostic tests that could be applied in non-expert settings may now be greater than ever before. Since the sequencing of the M. leprae genome, many research groups have investigated the potential of M. leprae antigens in either serologic or cell mediated assays. Here we provide an overview of the nearly 200 recombinant single proteins that were investigated during the last decade for their potential to be applied in field-friendly tests for the early diagnosis of leprosy.</p>  a0305-7518