01417nas a2200277 4500000000100000008004100001260000900042653001500051653001900066653003200085653003100117653001100148653001200159653001600171653001600187100001400203700001600217700001600233700001200249700001800261245004400279300000900323490000700332520078600339022001401125 1975 d c197510aCalifornia10aGene Frequency10aHistocompatibility Antigens10aHistocompatibility Testing10aHumans10aleprosy10aLymphocytes10aPhilippines1 aSmith G S1 aWalford R L1 aShepard C C1 aPayne R1 aProchazka G J00aHistocompatibility antigens in leprosy. a42-90 v283 a
Results of HL-A typing are presented in 82 patients with leprosy and 50 normal Filipinos from Cebu, and 144 normal Filipino immigrants from the Luzon area. Comparisons of HL-A antigen frequencies among the total patients and normals of Cebu showed no statistically significant differences; however, HL-A10 was increased in frequency among the patients with lepromatous disease compared to the normals, and HL-A5 was increased among the tuberculoid patients compared to the lepromatous patients. None of these comparisons was statistically significant when corrected for the number of antigens tested. Comparisons of HL-A antigen frequencies between normal Filipinos of the Cebu and Luzon regions showed increased W-5 in the Luzon population (corrected p smaller than 0.025).
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