01438nas a2200349   4500000000100000008004100001260004200042653002200084653002400106653002200130653001100152653003100163653002500194653003100219653000900250653002500259653002100284653002200305653003000327653001300357653003100370653002500401100001800426700001300444700001500457700001800472245009900490300001000589490000700599520046800606022001401074       2012                            d  c2012 Mar-AprbElsevier Inc.aNew York10aAged, 80 and over10aDisease Progression10aFollow-Up Studies10aHumans10aImaging, Three-Dimensional10aLeprosy, lepromatous10aMagnetic Resonance Imaging10aMale10aMycobacterium leprae10aOrbital Diseases10aParanasal Sinuses10aSeverity of Illness Index10aSyndrome10aTomography, X-Ray Computed10aTrigeminal Neuralgia1 aEl Beltagi AH1 aEl-Nil H1 aAlrabiah L1 aEl Shammari N00aOrbital apex syndrome due to trigeminal perineural spread of sinonasal leprosy: a case report.  a142-50 v363 a<p>Leprosy is a granulomatous disease primarily affecting the skin and peripheral nerves caused by Mycobacterium leprae, but also significantly involving sinonasal cavities and cranial nerves. It continues to be a significant public health problem, and despite multidrug therapy, it can still cause significant morbidity. The awareness of cranial nerve, intracranial and orbital apex involvement as in our case is important for appropriate treatment measures.</p>  a1873-4499