01054nas a2200217   4500000000100000008004100001260001300042653001200055653001100067653001200078653002500090653001700115653001800132653001300150100001500163245006200178300001100240490000700251520056400258022001400822       1975                            d  c1975 Dec10aDapsone10aHumans10aleprosy10aMycobacterium leprae10aNasal Mucosa10aNose Diseases10aRifampin1 aBarton R P00aImportance of nasal lesions in early lepromatous leprosy.  a309-120 v573 a<p>There are some 20 million people in the world with leprosy. In the lepromatous form of the illness the nose becomes infected very early in the disease process. The nasal discharge which occurs is heavily bacillated and is the most potent source of exit of Mycobacterium leprae from the body. The necessity for early diagnosis and treatment of leprosy in the absence of an effective vaccine is discussed and the pathological changes that occur in the nose are outlined. The roles which the leprologist and the rhinologist are able to play are mentioned.</p>  a0035-8843