01838nas a2200397 4500000000100000008004100001260003700042653001500079653001000094653000900104653002200113653002300135653002500158653001100183653001100194653002100205653001200226653000900238653001600247653002500263653002800288653001600316100001400332700001400346700001500360700001400375700001700389700001400406700001100420245007100431856009100502300001000593490000700603520081600610022001401426 2011 d c2011 Oct bScielo aRio De Janeiro 10 aAdolescent 10 aAdult 10 aAged 10 aAged, 80 and over 10 aC-Reactive Protein 10 aCase-Control Studies 10 aFemale 10 aHumans 10 aInterferon-gamma 10 aleprosy 10 aMale 10 aMiddle Aged 10 aPeriodontal Diseases 10 aStomatognathic Diseases 10 aYoung Adult 1 aMotta ACF 1 aFurini RB 1 aSimão JCL 1 aVieira MB 1 aFerreira MAN 1 aKomesu MC 1 aFoss N 00 aCould leprosy reaction episodes be exacerbated by oral infections? uhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000500022&nrm=iso a633-5 0 v44 3 aINTRODUCTION: This study evaluated whether leprosy reactions could be associated with oral infection.
METHODS: Leprosy patients (n = 38) with (Group I) and without (Group II) oral infections were selected. Reactions were identified from the clinical and histopathological features associated with serum C-reactive protein (CRP) and10kDa interferon-gamma-induced protein (IP-10) levels, determined before and after elimination of the foci of infection.
RESULTS: Group I presented more reactions than group II did, and improvement of the reactions after dental treatment. Serum CRP and IP-10 did not differ before and after the dental treatment, but differed between the groups.
CONCLUSIONS: Oral infection could be an exacerbating factor in leprosy reactions.
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