02032nas a2200373   4500000000100000008004100001260001300042653001000055653002100065653000900086653000800095653001400103653001600117653001100133653001100144653000800155653001200163653000900175653001600184653001600200653001500216653001700231653003000248653001500278653001700293100001200310245006300322856005900385300001000444490000700454050003200461520115100493022001401644       2000                            d  c2000 Sep10aAdult10aAge Distribution10aAged10aArm10aCausality10aComorbidity10aFemale10aHumans10aLeg10aleprosy10aMale10aMiddle Aged10aProbability10aRecurrence10aRisk Factors10aSeverity of Illness Index10aSkin Ulcer10aTime Factors1 aKunst H00aPredisposing factors for recurrent skin ulcers in leprosy.  uhttp://leprev.ilsl.br/pdfs/2000/v71n3/pdf/v71n3a17.pdf  a363-80 v71  aInfolep Library - available3 a<p>This study was designed to determine the factors associated with recurrence of leprosy ulcers. Between April and August 1992, 55 consecutive leprosy patients admitted with skin ulcers were studied. Factors predisposing to recurrence, e.g. patient's age, disease duration, ulcer site, ulcer depth and physical deformity (taking into account neuromuscular and skeletal damage) were evaluated. Ulcer recurrence occurred in 40/55 (75%) patients. Recurrent ulceration was associated with location in the lower extremity (P = 0.02), where recurrences were more common in the midfoot and heel (P = 0.01). Recurrence was also associated with severity of physical deformity (P = 0.01), which increased the odds of recurrent ulceration by 4.2 times (95% confidence interval, 1.01-18.3). The severity of physical deformity itself was associated with the age of the patient (P = 0.04) and the disease duration (P = 0.02). In conclusion, there is a need to focus on identification of risk factors for recurrent leprosy ulceration. Targeted prevention strategies would be required if morbidity associated with recurrent skin ulceration is to be avoided.</p>  a0305-7518