01303nas a2200385 4500000000100000008004100001260001300042653002100055653002000076653002200096653001100118653001300129653001600142653001600158653001100174653001000185653000900195653002700204653002700231653002200258653003300280100001500313700001500328700001500343700001200358700001500370700001300385700001500398245009300413856005800506300001200564490000700576520032000583022001400903 2011 d c2011 Sep10aCluster Analysis10aCross Infection10aDisease Outbreaks10aFemale10agenotype10aHepacivirus10aHepatitis C10aHumans10aJapan10aMale10aMolecular Epidemiology10aSequence Analysis, DNA10aSequence Homology10aViral Nonstructural Proteins1 aTeramoto H1 aShiogama K1 aMizutani Y1 aInada K1 aKamahora T1 aMakino M1 aTsutsumi Y00aMolecular epidemiology of a hepatitis C virus outbreak in a leprosy sanatorium in Japan. uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165632/ a3358-600 v493 a

The hepatitis C virus (HCV) outbreak that occurred between 1940 and 1999 in a closed leprosy sanatorium located on a small island in Japan was analyzed. The analysis of 318 nucleotides in the NS5B region of HCV allowed us to establish the existence of at least three different HCV strains in this sanatorium.

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