01621nas a2200313   4500000000100000008004100001260001700042653001500059653001000074653000900084653003000093653001100123653001100134653002300145653001200168653000900180653001600189653002200205653000900227100001500236700001200251700001600263700001500279245008400294300000900378490000700387520089900394022001401293       2011                            d  c2011 Jan-Mar10aAdolescent10aAdult10aAged10aDrug Therapy, Combination10aFemale10aHumans10aLeprostatic Agents10aleprosy10aMale10aMiddle Aged10aPeripheral nerves10aSkin1 aPorichha D1 aRao A K1 aNehemaiah E1 aMishra M C00aResponse of thickened nerve trunks and skin lesions of leprosy patients to MDT.  a31-50 v833 a<p>This paper indicates the responses of thickened nerve trunks in leprosy patients to MDT. Out of 1625 cases, 557 (34.2%) cases had thickened nerve trunks at the time of registration. From these cases, 175 (31.4%) were randomly selected and re-examined by personal visit about 5 years after RFT. Follow-up showed persistent thickening in 96 (54.8%) cases. Persistence of nerve thickening was higher in MB leprosy. Additional nerve thickening appeared in 8 (4.6%) cases. New disability developed in 6 (3.4%) cases after RFT but these persons did not come for check up voluntarily. Reaction occurred in 6 during follow-up. Both MB and PB considered together thickening continued in as high as 96 (54.8%) compared to persisting skin lesions in 24 (13.7%) cases. Persons with thickened nerve trunks require more counseling to report for check up at the earliest sign of nerve function deficit.</p>  a0254-9395