01988nas a2200445   4500000000100000008004100001260001300042653001000055653001100065653001900076653001100095653001400106653001100120653002000131653002600151653002800177653002800205653000900233653001600242653001600258653001700274653001600291100001200307700001200319700001200331700001100343700001400354700001100368700001400379700001200393700001500405700001500420245008100435856005800516300001100574490000700585050001500592520092100607022001401528       2011                            d  c2011 Jul10aAdult10aBrazil10aCohort Studies10aFemale10aHematuria10aHumans10aKidney Diseases10aKidney Function Tests10aLeprosy, Multibacillary10aLeprosy, Paucibacillary10aMale10aMiddle Aged10aProteinuria10aRisk Factors10aYoung Adult1 aDaher E1 aSilva G1 aCezar L1 aLima R1 aGurjão N1 aMota R1 aAbreu KLS1 aRocha N1 aOliveira M1 aLibório A00aRenal dysfunction in leprosy: a historical cohort of 923 patients in Brazil.  uhttp://tdo.sagepub.com/content/41/3/148.full.pdf+html  a148-500 v41  aDAHER 20113 a<p>We investigated the factors associated with renal dysfunction in leprosy patients from Brazil. We report on a historical cohort of leprosy patients followed in two hospitals in Fortaleza City in northeastern Brazil. The factors associated with renal dysfunction were investigated. A total of 923 patients were included, with a mean age of 41.5 ± 19.1 years, and 53.3% were male. Renal dysfunction was found in 35 cases (3.8%). Proteinuria was found in 4.8% of cases, haematuria in 6.8% and leukocyturia in 10.4%. Factors associated with renal dysfunction by multivariate analysis were: reaction episode (odds ratio [OR] = 3.9, P = 0.03), multibacillary classification (OR = 3.5, P = 0.02) and advanced age (OR = 1.04, P = 0.01). Four patients (0.4%) died. Leprosy is associated with renal dysfunction, especially in older patients and those presenting with reaction episode and multibacillary classification.</p>  a1758-1133