01104nas a2200289   4500000000100000008004100001260001300042653001100055653001900066653003800085653001100123653002100134653001200155653002700167653002300194100001600217700001300233700002500246700002100271700001300292700001800305245010900323300001100432490000700443520035000450022001400800       2003                            d  c2003 Apr10aBrazil10aGene Frequency10aGenetic Predisposition to Disease10aHumans10aInterferon-gamma10aleprosy10aMicrosatellite Repeats10aMonte Carlo Method1 aReynard M P1 aTurner D1 aJunqueira-Kipnis A P1 aRamos de Souza M1 aMoreno C1 aNavarrete C V00aAllele frequencies for an interferon-gamma microsatellite in a population of Brazilian leprosy patients.  a149-510 v303 a<p>A group of Brazilian leprosy patients and controls were genotyped for a CA-repeat microsatellite polymorphism within the interferon (IFN)-gamma gene. A significantly higher frequency of alleles 5-7 was observed in this patient population, indicating that IFN-gamma gene polymorphism may contribute to the course of leprosy post-infection.</p>  a0960-7420