02134nas a2200469 4500000000100000008004100001260001300042653001400055653002600069653002000095653002900115653001900144653003800163653001700201653003400218653001700252653001100269653001500280653001500295653002100310653001100331653001300342653001200355653001800367653002400385653002300409653003300432653002200465653005400487653001600541653001300557653001300570100001300583700001300596700001500609700001200624245007800636300001200714490000700726520091700733022001401650 2010 d c2010 Dec10aAlkaloids10aAnti-Bacterial Agents10aAnti-HIV Agents10aAnti-Inflammatory Agents10aAntidiarrheals10aAntineoplastic Agents, Phytogenic10aAntioxidants10aCentral Nervous System Agents10aChymotrypsin10aFemale10aFlavonoids10aGlycosides10aHemolytic Agents10aHumans10aIridoids10aLignans10aMagnoliopsida10aMolecular Structure10aParasympatholytics10aPhosphodiesterase Inhibitors10aPlants, Medicinal10aProtein Tyrosine Phosphatase, Non-Receptor Type 110aSnake Bites10aSteroids10aTerpenes1 aBadoni R1 aSemwal D1 aKothiyal S1 aRawat U00aChemical constituents and biological applications of the genus Symplocos. a1069-800 v123 a

The genus Symplocos has been reviewed for its chemical constituents and biological activities including traditional importance of some common species. The plants of this genus contain terpenoids, flavonoids, lignans, phenols, steroids, alkaloids, and iridoids. Terpenoids are the major constituents within the genus Symplocos and most of them exhibit antiproliferative effects. Some phenolic glycoside derivatives showed inhibitory activity against snake-venom phosphodiesterase I and human nucleotide pyrophosphatase phosphodiesterase I. The members of genus Symplocos are well known for their traditional uses in the treatment of various diseases like leprosy, gynecological disorders, ulcers, leucorrhea, menorrhagia, malaria, and tumefaction. The aim of the present paper is to review the comprehensive knowledge of the plants of this genus including the traditional uses, chemistry, and pharmacology.

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