02018nas a2200325   4500000000100000008004100001260000900042653002600051653002900077653002800106653003000134653002200164653001100186653002300197653001200220653002500232653001300257653001500270653003000285653002200315100001400337700001300351700001300364700002000377245009700397300001000494490000700504520116700511022001401678       1999                            d  c199910aAnti-Bacterial Agents10aAnti-Inflammatory Agents10aDecompression, Surgical10aDrug Therapy, Combination10aFollow-Up Studies10aHumans10aLeprostatic Agents10aleprosy10aLeprosy, lepromatous10aNeuritis10aPrednisone10aSeverity of Illness Index10aTreatment Outcome1 aBoucher P1 aMillan J1 aParent M1 aMoulia-Pela J P00a[Randomized controlled trial of medical and medico-surgical treatment of Hansen's neuritis].  a171-70 v113 a<p>The aim of the study was to compare the results of the medical treatment alone and of the medico-surgical treatment on leprous neuritis. The patients were followed-up during 2 years, with regular neurological evaluations. The statistical study was performed using the Tukey test. Ninety-three nerves (ulnar, median, common peroneal and posterior tibial) with a deficit of less than 6 months duration have been studied in 31 leprosy patients. All the patients were treated by steroids but in some of them a nerve surgical decompression was performed. An improvement of the sensitive and motor deficit was observed in both groups. No significant statistical differences appeared between the 2 groups according to the nerve involved, the duration of the deficit, the form of leprosy and the type of antibacillary treatment. However, the medico-surgical treatment had a significant better result on pain and on major but incomplete nervous involvement. This study included a limited number of nerves, thus, it would be useful to perform others randomized assays to better define the indications of surgical decompression in the management of leprous neuritis.</p>  a0001-5938