01461nas a2200301 4500000000100000008004100001260000900042653001200051653002400063653001500087653003200102653001100134653001300145653001200158653001500170653001700185653001400202100001300216700001600229700001400245700001500259245012000274856008300394300001100477490000700488520065000495022001401145 1975 d c197510aAnimals10aAntigens, Bacterial10aArmadillos10aEvaluation Studies as Topic10aHumans10aLepromin10aleprosy10aSkin Tests10aTime Factors10aXenarthra1 aConvit J1 aPinardi M E1 aAvila J L1 aAranzazu N00aSpecificity of the 48-hour reaction to Mitsuda antigen. Use of a soluble antigen from human and armadillo lepromin. uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366352/pdf/bullwho00464-0063.pdf a187-910 v523 a
Two antigens were tested and compared in relation to the 48-h Fernandez reaction. They were obtained from standard human and from standard armadillo lepromin. All the tests were negative in patients with lepromatous leprosy and highly positive in those with tuberculoid leprosy and in lepromin-positive contacts. There was total agreement in all tests done with the two types of antigen. The antigenic component has the following basic properties: it precipitates with 80% saturated ammonium sulfate; it is not destroyed by autoclaving or by treatment with 0.4% phenol; it is non-dialysable; and it is destroyed by treatment with trypsin.
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