01362nas a2200241   4500000000100000008004100001260000900042653001100051653002100062653002100083653002100104653002000125653001200145653002400157100001800181700001600199700001300215245011500228300001000343490000800353520074500361022001401106       1976                            d  c197610aHumans10aImmunoglobulin A10aImmunoglobulin G10aImmunoglobulin M10aImmunoglobulins10aleprosy10aAlpha 1-Antitrypsin1 aCelikoglu S I1 aGöksel F M1 aBilgin T00aA preliminary report on a study of serum alpha-1-antitrypsin and immunoglobulin levels in lepromatous leprosy.  a125-80 v2783 a<p>IgG, IgA, and IgM immunoglobulins and alpha-1-antitrypsin globulin in sera from 30 patients with lepromatous leprosy were determined and compared with 30 age- and sex-matched healthy controls. Mean levels of IgG, IgM, IgA, and alpha-1-antitrypsin were significantly elevated in the sera of lepromatous leprosy patients in comparison with levels found in normal subjects. Statistical analysis of the relationships between levels of alpha-1-antitrypsin and immunoglobulins in the sera of lepromatous leprosy patients and controls revealed no correlation. It is therefore concluded that factors responsible for concentrations of immunoglobulins and alpha-1-antitrypsin are independent of each other in patients with lepromatous leprosy.</p>  a0077-8923