01735nas a2200445 4500000000100000008004100001260001300042653001000055653000900065653001300074653001900087653001800106653002300124653002400147653002500171653002500196653001100221653001100232653001200243653001300255653001200268653002000280653002600300653000900326653001600335653000900351653001800360100001200378700001800390700001400408700001300422700001600435700001400451700001400465245006400479300001200543490000800555520071200563022001401275 1976 d c1976 Jun10aAdult10aAged10aAntigens10aAutoantibodies10aB-Lymphocytes10aDermatitis, Atopic10aDermatitis, Contact10aDinitrochlorobenzene10aDinitrofluorobenzene10aFemale10aHumans10aLectins10aLepromin10aleprosy10aLeukocyte Count10aLymphocyte Activation10aMale10aMiddle Aged10aSkin10aT-Lymphocytes1 aRea T H1 aQuismorio F P1 aHarding B1 aNies K M1 aDi Saia P J1 aLevan N E1 aFriou G J00aImmunologic responses in patients with lepromatous leprosy. a791-8000 v1123 a
Immunologic responses were measured in 46 patients with lepromatous leprosy. These patients were not distinguishable from controls on the basis of responses to soluble intradermal antigens, sensitization to contactants, peripheral blood T- and B-cell percentages, in vitro lymphocyte responses to a mitogen, or the prevalence of autoantibodies. Generalized immunologic abnormalities in patients with lepromatous leprosy are neither predisposing causes nor necessary accompaniments of lepromatous leprosy, but are probably remote sequellae of the illness. By implication, the generalized immunologic abnormalities reported in other diseases are likely to be remote sequellae of the particular illness.
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