01237nas a2200277 4500000000100000008004100001260001300042653001100055653002000066653001100086653001200097653000900109653001700118653001400135653001900149653001700168653002400185653001600209100001800225245005800243856004100301300001100342490000700353520058500360022001400945 1997 d c1997 Sep10aFemale10aGlucocorticoids10aHumans10aleprosy10aMale10aMedian Nerve10aParalysis10aPeroneal Nerve10aPrednisolone10aProspective Studies10aUlnar nerve1 aSugumaran D S00aSteroid therapy for paralytic deformities in leprosy. uhttp://ila.ilsl.br/pdfs/v65n3a04.pdf a337-440 v653 a

One-hundred-forty-nine patients with 272 nerve paralyses, with visible deformity and gross disability, were prospectively followed up with steroid therapy. Out of 151 ulnar paralyses, 101 recovered (67%). Out of 52 median nerve paralyses, 45 recovered (86%); out of 69 foot drops, 54 recovered (78%) for an overall improvement of 73%. Serious side effects were few. Hence, steroid therapy should be widely encouraged for the treatment of early nerve damage to prevent permanent deformity/disability, and vigilance in spotting complications of steroid therapy is emphasized.

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