01552nas a2200301   4500000000100000008004100001260001300042653002500055653001900080653001600099653001100115653001200126653001000138653001900148653002500167653001800192653002000210653001100230100001800241700001800259700001500277245003100292300001100323490000700334050003200341520086300373022001401236       1977                            d  c1977 Apr10aAlanine Transaminase10aBlood Proteins10aCholesterol10aHumans10aleprosy10aLiver10aLiver Diseases10aLiver Function Tests10aSerum Albumin10aSerum Globulins10aThymol1 aGharpuray S M1 aGharpuray M B1 aKelkar S S00aLiver function in leprosy.  a216-200 v49  aInfolep Library - available3 a<p>Thirty eight patients of leprosy were classified on the basis of clinical and biopsy findings into 10 lepromatous (all reactional), 20 tuberculoid (7 in reaction) and 8 dimorphic (5 in reaction). The liver function tests--serum proteins, albumin/globulin ratio, fractions in paper electrophoresis, serum glutamic pyruvic transaminase (SGPT) and thymol turbidity tests--and the serum cholesterol was estimated in each patient. The abnormalities were a reversal of the albumin/globulin ratio in all the three groups and an increase in beta/globulin fraction in the lepromatous group, but total proteins were within normal limits. The thymol turbidity test showed moderately elevated levels in all three groups. SGPT was slightly raised in a few cases. Only a single patient with tuberculoid leprosy showed serum cholesterol to be over 250 mg per 100 ml.</p>  a0024-1024