01680nas a2200313   4500000000100000008004100001260001300042653001600055653001600071653002500087653001000112653002100122653001100143653001100154653001100165653002000176653000900196653002600205653002800231100001500259700001700274700001900291700001500310245012100325300001100446490000700457520088800464022001401352       1996                            d  c1996 Sep10aAge Factors10aBCG Vaccine10aCase-Control Studies10aChild10aChild, Preschool10aFemale10aHumans10aInfant10aInfant, Newborn10aMale10aSocioeconomic Factors10aTuberculosis, Meningeal1 aZodpey S P1 aMaldhure B R1 aShrikhande S N1 aTiwari R R00aEffectiveness of bacillus of Calmette-Guerin (BCG) vaccination against tuberculous meningitis: a case-control study.  a338-400 v943 a<p>A hospital-based pair-matched case-control study was carried out at Government Medical College Hospital, Nagpur to estimate the effectiveness of bacillus of Calmette-Guerin (BCG) vaccination against tuberculous meningitis. The study included 92 cases of tuberculous meningitis in the age group of 0-12 years and equal number of controls, matched for age, sex and socio-economic status. The protective effectiveness and prevented fraction were higher for the subjects in the age group of 0-6 years, males and subjects from upper strata of socio-economic class. The overall vaccine effectiveness and prevented fraction were estimated to be 86.54% (70.38-93.88%) and 65.54% (39.22-80.64%) respectively. Results of this study thus indicated that BCG vaccination was highly effective against tuberculous meningitis and played significant role in its prevention, in this population.</p>  a0019-5847