01830nas a2200313 4500000000100000008004100001260001300042653001500055653001000070653000900080653002200089653002600111653002600137653001100163653001100174653000900185653001600194653002900210653001300239100001200252700001600264700001800280700001700298245006800315300001100383490000700394520110100401022001401502 1996 d c1996 Dec10aAdolescent10aAdult10aAged10aAged, 80 and over10aAnti-Bacterial Agents10aArthritis, Infectious10aFemale10aHumans10aMale10aMiddle Aged10aStreptococcal Infections10aThailand1 aOsiri M1 aAkkasilpa S1 aReinprayoon S1 aDeesomchok U00aStreptococcal arthritis in Thai adults: case series and review. a755-610 v793 a

The incidence, clinical spectrum, types of streptococci in Thai adults with streptococcal arthritis in Chulalongkorn Hospital are similar to Western reports. The most frequently found organism was group A Streptococcus and the second was group G. Most of the patients were elderly who usually had underlying medical and/or joint diseases. There were 3 patients with underlying lepromatous leprosy which has never been reported before, while mixed types of streptococcal infection in the same joint, mixed types of streptococcal infection in the same patient and a patient with group C lumbar spondylodiskitis were also found. The most reliable diagnostic test is synovial fluid culture. All streptococcal isolates in our review were sensitive to penicillin and the clinical responses correlated with antibiotic sensitivity tests. Intravenous antibiotics and adequate drainage are the treatment of choice. The duration of treatment ranged from 4 to 6 weeks and most patients responded well. The overall mortality rate depended on host factors, organism virulence and treatment administered.

 a0125-2208