01347nas a2200349   4500000000100000008004100001260001300042653001200055653002600067653002200093653002400115653001800139653001800157653001600175653003800191653002100229653001300250653001200263653000900275653001300284653002500297653002500322653001800347100001400365700001400379700001400393245011300407300001000520490000700530520044600537022001400983       1997                            d  c1997 Mar10aAnimals10aAntibodies, Bacterial10aAntifungal Agents10aAntigens, Bacterial10aAntimalarials10aCell Membrane10aChloroquine10aEnzyme-Linked Immunosorbent Assay10aInterferon-gamma10aKinetics10aleprosy10aMice10aMonensin10aMycobacterium leprae10aRecombinant Proteins10aSchwann Cells1 aBirdi T J1 aD'Souza S1 aAntia N H00aExpression of mycobacterial antigens on murine dissociated Schwann cells infected with Mycobacterium leprae.  a181-50 v223 a<p>Mycobacterial antigens were detected in a cell surface ELISA on murine dissociated Schwann cells infected with Mycobacterium leprae. The time kinetics of expression and its refractoriness to modulation with monensin suggests that the antigens are likely to be integrated into the membrane during bacterial entry. This may be partially responsible for the defective Schwann cell functions leading to subsequent peripheral nerve damage.</p>  a0882-4010