01427nas a2200289 4500000000100000008004100001260001300042653001100055653002100066653001500087653001100102653001200113653001600125653001300141653001700154653000900171653002800180100001400208700001500222700001200237245008600249300000900335490000700344050003200351520074000383022001401123 1977 d c1977 Jan10aBiopsy10aEpithelial Cells10aEpithelium10aHumans10aleprosy10aLymphocytes10aNecrosis10aNerve Fibers10aSkin10aTuberculosis, Cutaneous1 aNirmala V1 aChacko C J1 aJob C K00aTuberculoid leprosy and tuberculosis skin: a comparative histopathological study. a65-90 v49 aInfolep Library - available3 a

Since it has been found hard to differentiate histopathologically tuberculoid leprosy from tuberculosis of the skin, a study of 20 biopsies from each of those conditions was undertaken to identify if possible some of their characteristic features. In tuberculoid leprosy along with tuberculoid granulomata there is always selective involvement and destruction of nerves, lack of fibrosis, absence of caseous necrosis and often epidermal atrophy. In cutaneous tuberculosis, on the other hand, in addition to tuberculous granuloma, there is often a proliferation reaction of the epidermis, areas of ulceration, absence of nerve destruction, marked increase in the reticulin, significant fibrosis and occasionally caseous necrosis.

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