01383nas a2200265   4500000000100000008004100001260001300042653001000055653000800065653002000073653003000093653002300123653001100146653001200157653001600169653002500185100001700210700001300227245003600240856004100276300000900317490000700326520077000333022001401103       2000                            d  c2000 Mar10aAdult10aEye10aEye Enucleation10aEye Infections, Bacterial10aHistocytochemistry10aHumans10aleprosy10aMacrophages10aMycobacterium leprae1 aEbenezer G J1 aDaniel E00aPathology of a lepromatous eye.  uhttp://ila.ilsl.br/pdfs/v68n1a04.pdf  a23-60 v683 a<p>Histopathological examination of an enucleated eye from a lepromatous leprosy patient showed the cornea, ciliary body, and part of the choroid to be infiltrated by macrophages filled with Mycobacterium leprae. The walls of blood vessels in the sclera, ciliary body and the anterior choroid demonstrated the presence of M. leprae, giving credence to the blood-borne entry of M. leprae into the eye. Unlike the eyes of experimental animals infected with M. leprae, histopathological study of this eye from a lepromatous leprosy patient demonstrated that M. leprae, although demonstrable in the anterior choroid, could not be found in the posterior parts of the eye, substantiating the claim that leprosy does not affect the posterior parts of the eye directly.</p>  a0148-916X