01361nas a2200385   4500000000100000008004100001260000900042653003300051653003000084653001800114653001100132653002300143653001200166653001500178100001700193700001400210700001200224700001400236700001500250700001600265700001200281700001600293700001700309700002000326700001700346700001200363700001500375700001700390245007900407856008500486300001100571490000700582520037200589022001400961       1996                            d  c199610aCommunicable Disease Control10aDrug Therapy, Combination10aGlobal health10aHumans10aLeprostatic Agents10aleprosy10aPrevalence1 aNoordeen S K1 aRoxas M G1 aFine PE1 aSmith W C1 aFeenstra P1 aGokhale S D1 aJoo L K1 aHuan-Ying L1 aKhalafalla G1 aBecx-Bleumink M1 aSrinivasan H1 aRao C K1 aLechat M F1 aSansarricq H00aEliminating leprosy as a public health problem--is the optimism justified?  uhttp://apps.who.int/iris/bitstream/10665/49255/1/WHF_1996_17%282%29_p109-144.pdf  a109-440 v173 a<p>Systematic use of multidrug therapy has proved to be so effective that leprosy can be eliminated as a public health problem by the end of the century. However, because of the long incubation period of this disease, together with the time-lag in case detection, the factors involved in achieving and sustaining its elimination have to be very carefully defined.</p>  a0251-2432