01904nas a2200325   4500000000100000008004100001260001700042653001000059653001600069653000900085653001100094653001100105653001200116653000900128653001600137653001500153653002600168653002100194653001700215653002200232653001000254100001700264700001600281245007400297300001100371490000700382050001700389520115800406022001401564       1996                            d  c1996 Jul-Sep10aAdult10aAge Factors10aAged10aFemale10aHumans10aleprosy10aMale10aMiddle Aged10aRegistries10aRetrospective Studies10aSex Distribution10aSocial Class10aTreatment Outcome10aYemen1 aMekhlafi G A1 aal-Qubati Y00aRetrospective analysis of 194 leprosy cases in the Republic of Yemen.  a227-340 v68  aMEKHLAFI19963 a<p>A review of the case files of 194 leprosy patients registered at a representative skin and venereal diseases out-patient clinic was done to assess the epidemiological and clinical patterns of the disease in Yemen. Almost all patients came from the poorer social groups and there was clustering of patients around some families. About 55% of the patients were aged 20 to 39 years and about 35% were aged over 40 years at the time of detection. Males were affected about three times as females; in males MB cases occurred about twice as often as PB cases and 12% of the cases presented as pure neuritic leprosy. Reactions were noticed in 39 cases (20%), six having type 1 and 27 having type 2 reaction. Bacterial index (BI) among 123 positive cases ranged from 0.1 to 6, about 70% of these cases showing mean BI of more than 2.0. Patients' response to treatment (MDT) was very good and BI decreased by about 1.55 (+/-0.05) logs per year. About 50% of the patients had some disability (14% grade 1), and the disability rate among PB cases was about 70%. Our findings indicate the need for earlier diagnosis and better disability preventive measures.</p>  a0254-9395